Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 7/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | SHBG | P04278 | 2/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7165568 | 0.86 | STS (0.65) | STSHSD17B1ESR1LMNAMAPT | |
| SCHEMBL21356582 | 0.86 | STS (0.65) | STSHSD17B1ESR1LMNAMAPT | |
| SCHEMBL7186449 | 0.83 | HSD17B1 (0.43) | STSHSD17B1ESR1LMNAMAPT | |
| SCHEMBL5972928 | 0.81 | AKR1C3 (0.54) | STSHSD17B1ESR1LMNAMAPT | |
| SCHEMBL2452535 | 0.80 | SHBG (0.64) | STSHSD17B1ESR1LMNAMAPT | |
| SCHEMBL1257193 | 0.79 | SHBG (0.59) | STSHSD17B1ESR1LMNAMAPT | |
| SCHEMBL12888972 | 0.78 | ESR1 (0.75) | STSHSD17B1ESR1LMNAMAPT | |
| SCHEMBL14924234 | 0.78 | ESR1 (0.75) | STSHSD17B1ESR1LMNAMAPT | |
| SCHEMBL5525067 | 0.78 | ESR1 (0.75) | STSHSD17B1ESR1LMNAMAPT | |
| SCHEMBL1236350 | 0.78 | ESR1 (0.75) | STSHSD17B1ESR1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998014194-A1 | STEROIDS AS NEUROCHEMICAL STIMULATORS OF THE VNO TO ALLEVIATE SYMPTOMS OF ANXIETY | PHERIN PHARMACEUTICALS (US) | 1998-04-09 | — | — | WO | disclosed |
| WO-1997036596-A9 | STEROIDS AS NEUROCHEMICAL INITIATORS OF CHANGE IN HUMAN BLOOD LEVELS OF LH OR FSH | — | 1997-12-04 | — | — | WO | disclosed |
| WO-1997036596-A1 | STEROIDS AS NEUROCHEMICAL INITIATORS OF CHANGE IN HUMAN BLOOD LEVELS OF LH OR FSH | PHERIN PHARMACEUTICALS, INC. (US) | 1997-10-09 | — | — | WO | disclosed |