Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709417 | 0.90 | ALDH1A1 (0.39) | LMNAMMP2MMP9KMT2AMEN1 | |
| SCHEMBL8711029 | 0.87 | LMNA (0.35) | LMNAMMP2MMP9KMT2AMEN1 | |
| SCHEMBL8705630 | 0.86 | LMNA (0.42) | LMNAMMP2MMP9KMT2AGAA | |
| SCHEMBL8705961 | 0.85 | KMT2A (0.44) | LMNAKMT2AMEN1CYP1A2POLB | |
| SCHEMBL8704499 | 0.84 | OPRM1 (0.39) | LMNAMMP2MMP9KMT2AMEN1 | |
| SCHEMBL8708829 | 0.81 | CCR1 (0.46) | LMNAKMT2AMEN1CYP1A2POLB | |
| SCHEMBL8710937 | 0.78 | ALDH1A1 (0.37) | LMNAMMP2MMP9KMT2AMEN1 | |
| SCHEMBL8709426 | 0.75 | KMT2A (0.43) | LMNAKMT2ATSHRGAAOPRM1 | |
| SCHEMBL8710396 | 0.74 | LMNA (0.42) | LMNAKMT2AMEN1CYP1A2POLB | |
| SCHEMBL8705859 | 0.73 | CCR1 (0.45) | KMT2AMEN1POLBOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998002432-A1 | BICYCLIC COMPOUNDS FOR CONTROLLING MICTURITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-22 | — | — | WO | disclosed |