Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711029 | 0.90 | LMNA (0.35) | LMNAOPRM1MEN1KMT2ATSHR | |
| SCHEMBL8709417 | 0.88 | ALDH1A1 (0.39) | ALDH1A1MAPK10LMNAOPRM1PARP1 | |
| SCHEMBL8706705 | 0.85 | OPRM1 (0.39) | LMNAOPRM1MEN1KMT2ATSHR | |
| SCHEMBL8710396 | 0.84 | LMNA (0.42) | LMNAOPRM1HTTMEN1KMT2A | |
| SCHEMBL8709426 | 0.83 | KMT2A (0.43) | ALDH1A1MAPK10LMNAOPRM1PARP1 | |
| SCHEMBL8705859 | 0.80 | CCR1 (0.45) | MEN1KMT2APOLBOPRL1 | |
| SCHEMBL8711463 | 0.80 | DRD2 (0.51) | — | |
| SCHEMBL8710606 | 0.78 | LMNA (0.35) | LMNAOPRM1MEN1KMT2ATSHR | |
| SCHEMBL8705961 | 0.72 | KMT2A (0.44) | ALDH1A1MAPK10LMNAMEN1KMT2A | |
| SCHEMBL8705630 | 0.72 | LMNA (0.42) | LMNAOPRM1HTTKMT2AMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998002432-A1 | BICYCLIC COMPOUNDS FOR CONTROLLING MICTURITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-22 | — | — | WO | disclosed |