Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707491 | 0.86 | HTR2C (0.49) | HTR2CHTR2BPDE4B | |
| SCHEMBL8713108 | 0.80 | SHMT2 (0.59) | HTR2CHTR2BSHMT2QPCTMAPT | |
| SCHEMBL8713534 | 0.75 | LMNA (0.48) | HTR2CHTR2BSHMT2QPCTHTR7 | |
| SCHEMBL8714452 | 0.70 | L3MBTL1 (0.50) | SHMT2CYP2C9NR1H2NR1H3L3MBTL1 | |
| SCHEMBL7696958 | 0.69 | PDE4B (0.49) | HTR2CHTR2BQPCTPDE4B | |
| SCHEMBL8711923 | 0.69 | QPCT (0.52) | SHMT2QPCTMAPTNR1H2NR1H3 | |
| SCHEMBL8714432 | 0.69 | HTR2C (0.49) | HTR2CHTR2BQPCTPDE4BNR1H2 | |
| SCHEMBL8711866 | 0.68 | HTR2C (0.53) | HTR2CHTR2BPDE4B | |
| SCHEMBL8713095 | 0.68 | PDE4B (0.47) | HTR2CHTR2BQPCTPDE4BNR1H2 | |
| SCHEMBL8707308 | 0.68 | RAB9A (0.69) | QPCTMAPTNR1H2NR1H3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042666-A1 | NOVEL 3,4-DIALKOXYPHENYL DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1998-10-01 | — | — | WO | disclosed |