Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 3/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711675 | 0.95 | HTR2A (0.51) | HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL8713474 | 0.92 | ACHE (0.52) | PTGIRHTR2AHTR2CHTR7HTR6 | |
| SCHEMBL8714782 | 0.90 | OPRM1 (0.53) | PTGIROPRM1ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL8711020 | 0.86 | HSD11B1 (0.58) | PTGIROPRM1ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL8713336 | 0.86 | HSD11B1 (0.45) | HSD11B1HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL8716461 | 0.86 | HSD11B1 (0.55) | PTGIRALDH1A1SMN1; SMN2HSD11B1HTR2A | |
| SCHEMBL8711150 | 0.86 | MEN1 (0.53) | PTGIROPRM1ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL8713340 | 0.85 | HTR2C (0.45) | HSD11B1HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL8715993 | 0.85 | HTR2A (0.50) | HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL8710989 | 0.85 | HTR2A (0.56) | HTR2AHTR2CHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728835-A | HYPOTENSIVE AGENTS; ANTIISCHEMIC AGENTS | TOA EIYO, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0661266-A1 | Substituted cyclic amine compounds as 5HT2 antagonists | TOA EIYO LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |