Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716933 | 0.81 | THRB (0.63) | THRBHTTMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8714082 | 0.80 | THRB (0.62) | THRBHTTMAPTMEN1KMT2A | |
| SCHEMBL8901182 | 0.77 | HTT (0.67) | LMNAXDHTHRBHTTAKR1C3 | |
| SCHEMBL8901190 | 0.77 | HTT (0.67) | LMNAXDHTHRBHTTAKR1C3 | |
| SCHEMBL8901198 | 0.77 | HTT (0.67) | LMNAXDHTHRBHTTAKR1C3 | |
| Hydrochloric Acid SCHEMBL8712061 | 0.67 | THRB (0.52) | THRBHTTMAPTMEN1KMT2A | |
| SCHEMBL8711566 | 0.67 | THRB (0.51) | THRBHTTMAPTMEN1KMT2A | |
| SCHEMBL8714601 | 0.67 | THRB (0.51) | THRBHTTMAPTMEN1KMT2A | |
| SCHEMBL7965236 | 0.65 | ALDH1A1 (0.57) | LMNAXDHAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7245118 | 0.65 | NPC1 (0.51) | LMNAXDHAKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830902-A | SQUALENE SYNTHASE INHIBITOR | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |