Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.42 |
| ▸ | CNR2 | P34972 | 6/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717501 | 0.84 | MPO (0.53) | MPOMTNR1AMTNR1BHPGDTSHR | |
| SCHEMBL8712366 | 0.83 | MPO (0.46) | MPOMTNR1AMTNR1BCNR2CNR1 | |
| SCHEMBL8711714 | 0.75 | MPO (0.51) | MPOMTNR1AMTNR1BHPGD | |
| SCHEMBL8715083 | 0.74 | KDM4E (0.53) | MPOMTNR1AMTNR1BHPGD | |
| SCHEMBL8712074 | 0.72 | MPO (0.47) | MPOMTNR1AMTNR1BHPGDTRPV1 | |
| SCHEMBL7055582 | 0.70 | MTNR1A (0.39) | MTNR1AMTNR1BHPGD | |
| SCHEMBL8717169 | 0.69 | MTNR1A (0.65) | MPOMTNR1AMTNR1BHPGDTRPV1 | |
| SCHEMBL8712198 | 0.69 | MPO (0.65) | MPOMTNR1AMTNR1BHPGDTRPV1 | |
| SCHEMBL8717161 | 0.68 | MTNR1A (0.76) | MPOMTNR1AMTNR1BHPGD | |
| SCHEMBL24693005 | 0.67 | MPO (0.42) | MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770610-A | ADMINISTERING R-(+)-N-(2-METHYL-2-(5-METHOXY-6-CHLOROINDOL-3-YL)ETHYL) ACETAMIDE | ELI LILLY AND COMPANY (US) | 1998-06-23 | — | — | US | disclosed |