Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MPO | P05164 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714799 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL8716716 | 0.83 | KDM4E (0.48) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL8717763 | 0.81 | KDM4E (0.46) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL7891065 | 0.79 | MTNR1A (0.54) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL8711894 | 0.74 | MPO (0.53) | HPGDMPOMTNR1AMTNR1B | |
| SCHEMBL8715597 | 0.73 | MTNR1A (0.67) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL8717501 | 0.72 | MPO (0.53) | KDM4EMEN1KMT2AHCRTR1HPGD | |
| SCHEMBL8711714 | 0.70 | MPO (0.51) | KDM4EMEN1KMT2AHCRTR1MAPT | |
| SCHEMBL7058321 | 0.70 | MTNR1A (0.49) | MTNR1AMTNR1B | |
| SCHEMBL23417935 | 0.69 | ALDH1A1 (1.00) | KDM4EALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770610-A | ADMINISTERING R-(+)-N-(2-METHYL-2-(5-METHOXY-6-CHLOROINDOL-3-YL)ETHYL) ACETAMIDE | ELI LILLY AND COMPANY (US) | 1998-06-23 | — | — | US | disclosed |