Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 3/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711894 | 0.84 | MPO (0.53) | MPOMTNR1AMTNR1BTSHRHPGD | |
| SCHEMBL8711714 | 0.81 | MPO (0.51) | MPOMTNR1AMTNR1BHPGDMEN1 | |
| SCHEMBL8712366 | 0.78 | MPO (0.46) | MPOMTNR1AMTNR1BTSHRHPGD | |
| SCHEMBL8712074 | 0.78 | MPO (0.47) | MPOMTNR1AMTNR1BHPGDMEN1 | |
| SCHEMBL8716716 | 0.76 | KDM4E (0.48) | MPOMTNR1AMTNR1BHPGDMEN1 | |
| SCHEMBL8717763 | 0.74 | KDM4E (0.46) | MPOHPGDMEN1KMT2AKDM4E | |
| SCHEMBL8717169 | 0.72 | MTNR1A (0.65) | MPOMTNR1AMTNR1BHPGDMEN1 | |
| SCHEMBL8715083 | 0.72 | KDM4E (0.53) | MPOMTNR1AMTNR1BHPGDMEN1 | |
| SCHEMBL10905707 | 0.71 | MTNR1A (0.65) | MPOMTNR1AMTNR1BHPGDMEN1 | |
| SCHEMBL7055230 | 0.70 | MTNR1A (0.44) | MTNR1AMTNR1BMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770610-A | ADMINISTERING R-(+)-N-(2-METHYL-2-(5-METHOXY-6-CHLOROINDOL-3-YL)ETHYL) ACETAMIDE | ELI LILLY AND COMPANY (US) | 1998-06-23 | — | — | US | disclosed |