Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 8/20 | 0.42 |
| ▸ | CA2 | P00918 | 8/20 | 0.42 |
| ▸ | CA9 | Q16790 | 7/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713437 | 1.00 | ALDH1A1 (0.46) | ALDH1A1HTTHTR6MEN1NR1I2 | |
| SCHEMBL8710866 | 1.00 | ALDH1A1 (0.46) | ALDH1A1HTTHTR6MEN1NR1I2 | |
| SCHEMBL8711065 | 1.00 | ALDH1A1 (0.46) | ALDH1A1HTTHTR6MEN1NR1I2 | |
| SCHEMBL8711016 | 1.00 | ALDH1A1 (0.46) | ALDH1A1HTTHTR6MEN1NR1I2 | |
| SCHEMBL8713475 | 0.98 | HTR6 (0.46) | ALDH1A1HTTHTR6MEN1NR1I2 | |
| SCHEMBL8716405 | 0.94 | HTR6 (0.47) | ALDH1A1HTTHTR6MEN1MAPT | |
| SCHEMBL8714605 | 0.87 | HTR6 (0.50) | HTR6MEN1MAPTKMT2ACA1 | |
| SCHEMBL16047004 | 0.85 | CA1 (0.48) | ALDH1A1LMNACYP3A4CA1CA2 | |
| SCHEMBL28481648 | 0.84 | LMNA (0.48) | ALDH1A1MEN1NR1I2LMNACHRM2 | |
| SCHEMBL29165399 | 0.83 | LMNA (0.42) | ALDH1A1MEN1NR1I2LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5717124-A | Process for preparation of oxyglutaric acid ester derivatives | UBE INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |