Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713475 | 0.95 | HTR6 (0.46) | HTR6MAPTHPGDNFE2L2KCNH2 | |
| SCHEMBL8711065 | 0.94 | ALDH1A1 (0.46) | HTR6MAPTHPGDNFE2L2KCNH2 | |
| SCHEMBL8710866 | 0.94 | ALDH1A1 (0.46) | HTR6MAPTHPGDNFE2L2KCNH2 | |
| SCHEMBL8713437 | 0.94 | ALDH1A1 (0.46) | HTR6MAPTHPGDNFE2L2KCNH2 | |
| SCHEMBL8711016 | 0.94 | ALDH1A1 (0.46) | HTR6MAPTHPGDNFE2L2KCNH2 | |
| SCHEMBL8712072 | 0.94 | ALDH1A1 (0.46) | HTR6MAPTHPGDNFE2L2KCNH2 | |
| SCHEMBL8714605 | 0.90 | HTR6 (0.50) | HTR6MAPTHPGDATML3MBTL1 | |
| SCHEMBL29415366 | 0.86 | CA2 (0.47) | HPGDL3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7190008 | 0.86 | CA2 (0.47) | HPGDL3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8713487 | 0.83 | HTR6 (0.53) | HTR6NFE2L2KCNH2ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5717124-A | Process for preparation of oxyglutaric acid ester derivatives | UBE INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |