Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 11/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | CTSE | P14091 | 1/20 | 0.43 |
| ▸ | PGC | P20142 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709813 | 1.00 | REN (0.43) | RENCTSDCTSEPGCKLK5 | |
| SCHEMBL8709818 | 1.00 | REN (0.43) | RENCTSDCTSEPGCKLK5 | |
| SCHEMBL8712611 | 0.90 | REN (0.53) | RENCTSDCTSEPGCKLK5 | |
| SCHEMBL8712609 | 0.90 | REN (0.53) | RENCTSDCTSEPGCKLK5 | |
| SCHEMBL8708969 | 0.85 | KLK5 (0.43) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8708966 | 0.85 | KLK5 (0.43) | KLK5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8709246 | 0.84 | REN (0.42) | RENKLK5 | |
| SCHEMBL8709243 | 0.84 | REN (0.42) | RENKLK5 | |
| SCHEMBL8711623 | 0.84 | REN (0.42) | RENKLK5 | |
| SCHEMBL6445403 | 0.81 | CTSD (0.57) | RENCTSDCTSEPGCKLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753652-A | Antiretroviral hydrazine derivatives | NOVARTIS CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |