Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 3/20 | 0.41 |
| ▸ | KLK1 | P06870 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 14/20 | 0.40 |
| ▸ | MMP3 | P08254 | 5/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401964 | 0.83 | MMP2 (0.40) | KLKB1KLK1MMP1MMP3MMP9 | |
| SCHEMBL6319663 | 0.78 | KLKB1 (0.40) | KLKB1KLK1MMP1MMP9MMP2 | |
| SCHEMBL6324563 | 0.72 | MMP3 (0.43) | KLKB1KLK1MMP1MMP3MMP9 | |
| SCHEMBL8918072 | 0.72 | KLKB1 (0.34) | KLKB1KLK1MMP1MMP9MMP2 | |
| SCHEMBL6317679 | 0.70 | MMP2 (0.37) | KLKB1KLK1MMP9MMP2 | |
| SCHEMBL6316746 | 0.69 | MMP1 (0.41) | MMP1MMP9ADAM17 | |
| SCHEMBL6326078 | 0.69 | S1PR1 (0.39) | KLKB1KLK1MMP1MMP3MMP9 | |
| SCHEMBL6318207 | 0.68 | KLKB1 (0.39) | KLKB1KLK1MMP1MMP3MMP9 | |
| SCHEMBL6318098 | 0.66 | MMP2 (0.36) | KLKB1KLK1MMP9MMP2 | |
| SCHEMBL6320709 | 0.66 | CYP1A2 (0.39) | KLKB1KLK1MMP3MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869974-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-10-14 | — | — | EP | claimed |