Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 3/20 | 0.34 |
| ▸ | KLK1 | P06870 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712529 | 0.86 | MMP2 (0.34) | KLKB1KLK1MMP2MMP9MMP8 | |
| SCHEMBL6319663 | 0.86 | KLKB1 (0.40) | KLKB1KLK1MMP2MMP9MMP8 | |
| SCHEMBL6317679 | 0.80 | MMP2 (0.37) | KLKB1KLK1MMP2MMP9MMP8 | |
| SCHEMBL6323433 | 0.79 | MMP2 (0.36) | KLKB1KLK1MMP2MMP9MMP8 | |
| SCHEMBL6318098 | 0.78 | MMP2 (0.36) | KLKB1KLK1MMP2MMP9MMP8 | |
| SCHEMBL7063361 | 0.76 | MMP2 (0.35) | KLKB1KLK1MMP2MMP9MMP8 | |
| SCHEMBL6318207 | 0.75 | KLKB1 (0.39) | KLKB1KLK1MMP2MMP9MMP8 | |
| SCHEMBL8712433 | 0.72 | KLKB1 (0.41) | KLKB1KLK1MMP2MMP9MMP1 | |
| SCHEMBL6324563 | 0.71 | MMP3 (0.43) | KLKB1KLK1MMP2MMP9CTSK | |
| SCHEMBL6316746 | 0.70 | MMP1 (0.41) | MMP9TACR1CTSLCTSSPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | claimed |