Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711984 | 0.91 | ALDH1A1 (0.55) | RXFP1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL8713847 | 0.88 | PRKDC (0.48) | RXFP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27512307 | 0.74 | ALDH1A1 (0.60) | RXFP1KDM4EALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL8711799 | 0.72 | CYP19A1 (0.48) | KDM4EALDH1A1HPGDL3MBTL1TSHR | |
| SCHEMBL7315229 | 0.71 | RXFP1 (0.69) | RXFP1KDM4EALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL26352438 | 0.70 | POLB (0.51) | KDM4EALDH1A1L3MBTL1HSD17B10TSHR | |
| SCHEMBL5409829 | 0.69 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL30634404 | 0.69 | ALOX15 (0.50) | RXFP1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL8388243 | 0.69 | TSHR (0.54) | KDM4EALDH1A1HPGDL3MBTL1HSD17B10 | |
| SCHEMBL2214591 | 0.68 | GAA (0.50) | KDM4EALDH1A1HPGDL3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842176-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-05-20 | — | — | EP | claimed |
| WO-1997005137-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-02-13 | — | — | WO | claimed |
| EP-0842176-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997005137-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-02-13 | — | — | WO | disclosed |