Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PIK3C2B | O00750 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712545 | 0.88 | RXFP1 (0.54) | PRKDCPKMNPSR1POLBALDH1A1 | |
| SCHEMBL8711984 | 0.77 | ALDH1A1 (0.55) | PKMNPSR1ALDH1A1KDM4ERXFP1 | |
| SCHEMBL8711799 | 0.77 | CYP19A1 (0.48) | PRKDCPKMNPSR1POLBALDH1A1 | |
| SCHEMBL400114 | 0.72 | KDM4E (0.56) | NPSR1ALDH1A1KDM4EHDAC1HDAC6 | |
| SCHEMBL13752240 | 0.70 | PRKDC (0.57) | PRKDCPOLBALDH1A1KDM4EPIK3CD | |
| SCHEMBL4220258 | 0.70 | PKM (0.60) | PKMPOLBALDH1A1KDM4EPIK3CA | |
| SCHEMBL9584516 | 0.69 | POLB (0.51) | PRKDCPOLBALDH1A1HDAC1HDAC11 | |
| SCHEMBL8387165 | 0.68 | KMT2A (0.55) | PRKDCPOLBALDH1A1KDM4EHDAC1 | |
| SCHEMBL6902224 | 0.67 | CCR2 (0.67) | PRKDCPOLBPIK3C2BALDH1A1KDM4E | |
| SCHEMBL398278 | 0.67 | TSHR (0.53) | POLBALDH1A1KDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842176-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-05-20 | — | — | EP | claimed |
| WO-1997005137-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-02-13 | — | — | WO | claimed |
| EP-0842176-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997005137-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-02-13 | — | — | WO | disclosed |