Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 13/20 | 0.34 |
| ▸ | HTR1A | P08908 | 12/20 | 0.34 |
| ▸ | DRD2 | P14416 | 12/20 | 0.34 |
| ▸ | HTR7 | P34969 | 12/20 | 0.34 |
| ▸ | HTR6 | P50406 | 12/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7863415 | 0.93 | HTR2A (0.35) | ACHEHTR2AHTR1ADRD2HTR7 | |
| SCHEMBL7870234 | 0.88 | HDAC3 (0.32) | HTR2AHTR1ADRD2HTR7HTR6 | |
| Hydrochloric Acid SCHEMBL7871669 | 0.87 | HDAC3 (0.32) | HTR2AHTR1ADRD2HTR7HTR6 | |
| SCHEMBL7868936 | 0.85 | KCNH2 (0.33) | PIM1FLT3KCNH2PIM3PIM2 | |
| Hydrochloric Acid SCHEMBL7863474 | 0.84 | KCNH2 (0.32) | PIM1FLT3KCNH2PIM3PIM2 | |
| SCHEMBL8589168 | 0.82 | HTR7 (0.36) | HTR2AHTR1ADRD2HTR7HTR6 | |
| Hydrochloric Acid SCHEMBL8716045 | 0.81 | HTR7 (0.35) | HTR2AHTR1ADRD2HTR7HTR6 | |
| SCHEMBL8713773 | 0.81 | ACHE (0.34) | ACHEHTR2AHTR1ADRD2HTR7 | |
| SCHEMBL8708955 | 0.79 | HTR2A (0.35) | ACHEHTR2AHTR1ADRD2HTR7 | |
| SCHEMBL8713347 | 0.75 | HTR1A (0.34) | HTR2AHTR1ADRD2HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826686-A2 | Tricyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |