Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 13/20 | 0.35 |
| ▸ | HTR1A | P08908 | 12/20 | 0.35 |
| ▸ | DRD2 | P14416 | 12/20 | 0.35 |
| ▸ | HTR7 | P34969 | 12/20 | 0.35 |
| ▸ | HTR6 | P50406 | 12/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870234 | 0.94 | HDAC3 (0.32) | HTR2AHTR1ADRD2HTR7HTR6 | |
| Hydrochloric Acid SCHEMBL7871669 | 0.93 | HDAC3 (0.32) | HTR2AHTR1ADRD2HTR7HTR6 | |
| SCHEMBL8712933 | 0.93 | ACHE (0.35) | HTR2AHTR1ADRD2HTR7HTR6 | |
| SCHEMBL7868936 | 0.92 | KCNH2 (0.33) | PIM1FLT3KCNH2PIM3PIM2 | |
| Hydrochloric Acid SCHEMBL7863474 | 0.91 | KCNH2 (0.32) | PIM1FLT3KCNH2PIM3PIM2 | |
| SCHEMBL8708955 | 0.84 | HTR2A (0.35) | HTR2AHTR1ADRD2HTR7HTR6 | |
| SCHEMBL8589168 | 0.83 | HTR7 (0.36) | HTR2AHTR1ADRD2HTR7HTR6 | |
| Hydrochloric Acid SCHEMBL8716045 | 0.82 | HTR7 (0.35) | HTR2AHTR1ADRD2HTR7HTR6 | |
| Hydrochloric Acid SCHEMBL7870198 | 0.79 | IRAK4 (0.38) | PIM1 | |
| Hydrochloric Acid SCHEMBL7868715 | 0.79 | IRAK4 (0.38) | PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010051631-A1 | Tricyclic compounds, their production and use | TAKATANI MUNEO (JP) | 2001-12-13 | — | — | US | disclosed |
| US-6251905-B1 | Tricyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-26 | — | — | US | disclosed |
| US-5958942-A | HAVING EXCELLENT PDGF-INHIBITING ACTIVITIES, ANTIHYPERTENSIVE ACTIVITIES, ACTIVITIES OF AMELIORATING RENAL DISEASES AND ACTIVITIES OF LOWERING LIPID LEVEL. | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-28 | — | — | US | disclosed |
| EP-0826686-A2 | Tricyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010051631-A1 | Tricyclic compounds, their production and use | PDGFA, HGF, REN | HTR2A 313/4885HTR1A 239/4885DRD2 1720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.