Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.47 |
| ▸ | PLAU | P00749 | 8/20 | 0.42 |
| ▸ | PLG | P00747 | 6/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.42 |
| ▸ | PLAT | P00750 | 4/20 | 0.42 |
| ▸ | F2 | P00734 | 4/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905600 | 0.92 | ITGB3 (0.54) | ITGB3ITGA2BPLAUPLGPRSS1 | |
| SCHEMBL8903869 | 0.92 | ITGB3 (0.54) | ITGB3ITGA2BPLAUPLGPRSS1 | |
| SCHEMBL8905183 | 0.86 | CNR2 (0.41) | ITGB3ITGA2BPLAUITGAVCHRM2 | |
| SCHEMBL8713085 | 0.85 | ITGB3 (0.60) | ITGB3ITGA2BPLAUPLGPRSS1 | |
| SCHEMBL8903880 | 0.77 | F2 (0.41) | ITGB3ITGA2BPLAUPLGPRSS1 | |
| SCHEMBL8905568 | 0.77 | ITGB3 (0.68) | ITGB3ITGA2BPLAUPLGPRSS1 | |
| SCHEMBL8903850 | 0.77 | ITGB3 (0.68) | ITGB3ITGA2BPLAUPLGPRSS1 | |
| SCHEMBL8904848 | 0.75 | PLAU (0.48) | ITGB3ITGA2BPLAUPLGPRSS1 | |
| SCHEMBL8904886 | 0.75 | PLAU (0.49) | ITGB3ITGA2BPLAUPLGPRSS1 | |
| SCHEMBL8903960 | 0.74 | F2 (0.47) | ITGB3ITGA2BPLAUPLGPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |