Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.38 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719069 | 0.89 | KIF11 (0.39) | KIF11KCNJ6KCNJ5KCNJ3SLC6A2 | |
| SCHEMBL8713660 | 0.87 | SLC6A2 (0.41) | KIF11KCNJ6KCNJ5KCNJ3SLC6A2 | |
| SCHEMBL8713286 | 0.86 | TP53 (0.44) | KCNJ6KCNJ5KCNJ3CYP3A4CYP2C9 | |
| SCHEMBL8716735 | 0.86 | SLC6A2 (0.38) | KIF11SLC6A2SLC6A4SLC6A3TP53 | |
| SCHEMBL8718275 | 0.85 | KIF11 (0.37) | KIF11KCNJ6KCNJ5KCNJ3SLC6A2 | |
| SCHEMBL8717145 | 0.83 | SMN1; SMN2 (0.40) | KIF11SMN1; SMN2CXCR4LMNAGAA | |
| SCHEMBL8716588 | 0.82 | SLC6A2 (0.39) | KIF11SLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL8716625 | 0.80 | KIF11 (0.38) | KIF11SLC6A2SLC6A4PNMT | |
| SCHEMBL8716358 | 0.80 | GRIN2B (0.46) | KIF11KCNJ5KCNJ3SLC6A2SLC6A4 | |
| SCHEMBL8713910 | 0.79 | SLC6A2 (0.41) | KIF11SLC6A2SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |