Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713660 | 0.92 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6NFKB1 | |
| SCHEMBL8716735 | 0.90 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3GRIN2BKMT2A | |
| SCHEMBL8716358 | 0.89 | GRIN2B (0.46) | SLC6A2SLC6A4SLC6A3GRIN2BCYP3A4 | |
| SCHEMBL8716595 | 0.88 | PPARG (0.38) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8718275 | 0.86 | KIF11 (0.37) | SLC6A2SLC6A4SLC6A3GRIN2BCYP3A4 | |
| SCHEMBL8719069 | 0.85 | KIF11 (0.39) | SLC6A2SLC6A4SLC6A3PNMTKIF11 | |
| SCHEMBL8717467 | 0.84 | MEN1 (0.48) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8713910 | 0.83 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6NFKB1 | |
| SCHEMBL8713653 | 0.82 | KIF11 (0.38) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL8713286 | 0.81 | TP53 (0.44) | GRIN2BCYP3A4CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |