Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.43 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716588 | 0.89 | SLC6A2 (0.39) | GRIN2BSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL8713660 | 0.89 | SLC6A2 (0.41) | KCNJ5KCNJ3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8713286 | 0.89 | TP53 (0.44) | GRIN2BKCNJ5KCNJ3MC4RCYP3A4 | |
| SCHEMBL8716735 | 0.88 | SLC6A2 (0.38) | GRIN2BSLC6A2SLC6A4SLC6A3TP53 | |
| SCHEMBL8713638 | 0.85 | MEN1 (0.35) | GRIN2BSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL8718275 | 0.84 | KIF11 (0.37) | GRIN2BKCNJ5KCNJ3SLC6A2SLC6A4 | |
| SCHEMBL8715312 | 0.82 | MEN1 (0.41) | GRIN2BMC4RNR3C1NR3C2CACNA1G | |
| SCHEMBL8713910 | 0.81 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3NR3C1NR3C2 | |
| SCHEMBL8719069 | 0.81 | KIF11 (0.39) | KCNJ5KCNJ3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8716208 | 0.80 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |