SCHEMBL8716735

SCHEMBL8716735

Cc1ccc(C(C)(Cc2ccccc2Cl)C[C@H](N)O)cc1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KIF11 P52732 7/20 0.35
PNMT P11086 1/20 0.34
CTSK P43235 1/20 0.34
PKM P14618 1/20 0.33
GRIN2B Q13224 1/20 0.33
LMNA P02545 1/20 0.33
KMT2A Q03164 1/20 0.33
TAAR1 Q96RJ0 2/20 0.33
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8716588 0.90 SLC6A2 (0.39) SLC6A2SLC6A4SLC6A3KIF11PNMT
SCHEMBL8713660 0.90 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3KIF11PNMT
SCHEMBL8716358 0.88 GRIN2B (0.46) SLC6A2SLC6A4SLC6A3KIF11PNMT
SCHEMBL8713653 0.86 KIF11 (0.38) SLC6A2SLC6A4SLC6A3KIF11PNMT
SCHEMBL8718275 0.85 KIF11 (0.37) SLC6A2SLC6A4SLC6A3KIF11PNMT
SCHEMBL8713910 0.82 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3KIF11PNMT
SCHEMBL8713551 0.82 KIF11 (0.38) KIF11LMNAKMT2ATAAR1
SCHEMBL8719069 0.82 KIF11 (0.39) SLC6A2SLC6A4SLC6A3KIF11PNMT
SCHEMBL8714242 0.81 SLC6A2 (0.38) SLC6A2SLC6A4SLC6A3PNMTCTSK
SCHEMBL8716595 0.81 PPARG (0.38) KIF11GRIN2BLMNAKMT2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5811293-A CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-09-22 US disclosed