Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715549 | 0.81 | SMN1; SMN2 (0.51) | HTR2AHTR2CHTR2BPNMTPPARA | |
| SCHEMBL8715547 | 0.81 | SMN1; SMN2 (0.51) | HTR2AHTR2CHTR2BPNMTPPARA | |
| SCHEMBL10939547 | 0.81 | HTR2A (0.41) | ACP3HTR2AHTR2CHTR2BPNMT | |
| SCHEMBL8718507 | 0.80 | PNMT (0.46) | ACP3HTR2AHTR2CHTR2BPNMT | |
| SCHEMBL8718504 | 0.80 | PNMT (0.46) | ACP3HTR2AHTR2CHTR2BPNMT | |
| SCHEMBL8713281 | 0.79 | PNMT (0.45) | ACP3HTR2AHTR2CHTR2BPNMT | |
| SCHEMBL8713278 | 0.79 | PNMT (0.45) | ACP3HTR2AHTR2CHTR2BPNMT | |
| SCHEMBL8716245 | 0.79 | CYP2D6 (0.46) | PPARGPPARACYP2D6SIGMAR1SLC6A2 | |
| SCHEMBL8716247 | 0.79 | CYP2D6 (0.46) | PPARGPPARACYP2D6SIGMAR1SLC6A2 | |
| SCHEMBL8714019 | 0.78 | CYP2D6 (0.58) | EPHX1CYP2D6SIGMAR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |