Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716245 | 1.00 | CYP2D6 (0.46) | CYP2D6TRPA1SLC6A2TAAR1SLC6A4 | |
| SCHEMBL8714017 | 0.85 | CYP2D6 (0.58) | CYP2D6TRPA1SLC6A2TAAR1SLC6A4 | |
| SCHEMBL8714019 | 0.85 | CYP2D6 (0.58) | CYP2D6TRPA1SLC6A2TAAR1SLC6A4 | |
| SCHEMBL8713862 | 0.83 | PNMT (0.50) | CYP2D6TRPA1SLC6A2TAAR1SLC6A4 | |
| SCHEMBL8713926 | 0.79 | ADRA2A (0.49) | CYP2D6TRPA1SLC6A2TAAR1SLC6A4 | |
| SCHEMBL8713927 | 0.79 | ADRA2A (0.49) | CYP2D6TRPA1SLC6A2TAAR1SLC6A4 | |
| SCHEMBL8713768 | 0.79 | ACP3 (0.49) | CYP2D6SLC6A2SLC6A4SIGMAR1PPARG | |
| SCHEMBL7214546 | 0.77 | CNR2 (0.53) | SLC6A2SLC6A4CNR2SLC1A1MEN1 | |
| SCHEMBL8716602 | 0.77 | LMNA (0.49) | CYP2D6TRPA1SLC6A2TAAR1SLC6A4 | |
| SCHEMBL8716605 | 0.77 | LMNA (0.49) | CYP2D6TRPA1SLC6A2TAAR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |