Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPD | P32754 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998548 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP2C19HPGDCYP1A2CYP3A4 | |
| SCHEMBL9229472 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP2C19HPGDCYP1A2CYP3A4 | |
| SCHEMBL9871935 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19HPGDCYP1A2CYP3A4 | |
| SCHEMBL9711611 | 0.77 | HPD (0.49) | SMN1; SMN2CYP2C19HPGDCYP1A2CYP3A4 | |
| SCHEMBL8712107 | 0.75 | HPGD (0.46) | SMN1; SMN2CYP2C19HPGDCYP1A2CYP3A4 | |
| SCHEMBL9711579 | 0.74 | HPGD (0.41) | SMN1; SMN2CYP2C19HPGDCYP1A2CYP3A4 | |
| SCHEMBL9711511 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP2C19HPGDCYP1A2CYP3A4 | |
| SCHEMBL9191354 | 0.74 | HPD (0.67) | SMN1; SMN2CYP2C19HPGDCYP1A2CYP3A4 | |
| SCHEMBL8985982 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP2C19HPGDCYP1A2CYP3A4 | |
| SCHEMBL8985980 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP2C19HPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780626-A | HERBICIDES, ACARICIDES | SANDOZ, LTD (CH) | 1998-07-14 | — | — | US | disclosed |
| US-5728831-A | DECARBOXYLATION OF ALKOXYCARBONYLOXOOXAZINES | SANDOZ LTD. (CH) | 1998-03-17 | — | — | US | disclosed |
| US-5565410-A | 3-OXO-4-BENZOYL-5-OXY-2,3,4,6-TETRAHYDRO-1,2-OXAZINES; HERBICIDES; MITICIDES | SANDOZ LTD. (CH) | 1996-10-15 | — | — | US | disclosed |
| US-5336662-A | Herbicides | SANDOZ LTD. (CH) | 1994-08-09 | — | — | US | disclosed |
| EP-0394889-B1 | Heterocyclic diones as pesticides and plant growth regulators | SANDOZ AG (CH) | 1994-08-03 | — | — | EP | disclosed |
| EP-0394889-A2 | Heterocyclic diones as pesticides and plant growth regulators | SANDOZ AG (CH) | 1990-10-31 | — | — | EP | disclosed |