Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPD | P32754 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997025 | 0.88 | TSHR (0.38) | SMN1; SMN2POLBCYP3A4LMNAHPD | |
| SCHEMBL9871935 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19POLBHPGDCYP1A2 | |
| SCHEMBL997023 | 0.85 | HPD (0.36) | SMN1; SMN2POLBHPDNPC1RAB9A | |
| SCHEMBL9441394 | 0.83 | HPD (0.36) | SMN1; SMN2CYP2C19CYP1A2CYP3A4LMNA | |
| SCHEMBL997179 | 0.82 | HPD (0.40) | SMN1; SMN2HPD | |
| SCHEMBL8713774 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP2C19POLBHPGDCYP1A2 | |
| SCHEMBL9711511 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP2C19POLBHPGDCYP1A2 | |
| SCHEMBL9814693 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP2C19POLBHPGDCYP1A2 | |
| SCHEMBL1132003 | 0.78 | POLB (0.45) | SMN1; SMN2CYP2C19POLBHPGDCYP1A2 | |
| SCHEMBL9711611 | 0.74 | HPD (0.49) | SMN1; SMN2CYP2C19HPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614606-B1 | Herbicidal compositions | BASF AG (DE) | 2003-09-10 | — | — | EP | claimed |
| US-5990046-A | AGGREGATE AMOUNT OF A TRIKETONE OR DIONE HERBICIDE SUCH AS SULCOTRIONE, AND DIMETHENAMID IN A WEIGHT RATIO BETWEEN 1:2 AND 1:10; CONTROLLING WEEDS IN THE PRESENCE OF A CROP; IMPROVED HERBICIDAL ACTIVITY | SANDOZ LTD. (CH) | 1999-11-23 | — | — | US | claimed |
| US-5491124-A | PLANT GROWTH REGULATOR; CO-APPLICATION OF CERTAIN CHLOROACETAMIDES SELECTED FROM ACETOCHLOR AND METAZACHLOR AND ATLEAST ONE TRIKETONE SELECTED FROM SULCOTRIONE AND OTHERS | SANDOZ LTD. (CH) | 1996-02-13 | — | — | US | claimed |
| US-20140234225-A1 | METHOD OF TREATMENT USING NANOPARTICULATE COMPOSITIONS HAVING LYSOZYME AS A SURFACE STABILIZER | ALKERMES PHARMA IRELAND LIMITED (IE) | 2014-08-21 | — | — | US | disclosed |
| US-8652464-B2 | Method of treatment using nanoparticulate compositions having lysozyme as a surface stabilizer | ALKERMES PHARMA IRELAND LIMITED (IE) | 2014-02-18 | — | — | US | disclosed |
| US-20130224123-A1 | NANOPARTICULATE COMPOSITIONS HAVING LYSOZYME AS A SURFACE STABILIZER | ALKERMES PHARMA IRELAND LIMITED (IE) | 2013-08-29 | — | — | US | disclosed |
| US-8323641-B2 | Nanoparticulate compositions having lysozyme as a surface stabilizer | ALKERMES PHARMA IRELAND LIMITED (IE) | 2012-12-04 | — | — | US | disclosed |
| EP-2272342-B1 | Herbicidal compositions | BASF SE (DE) | 2012-06-27 | — | — | EP | disclosed |
| EP-2050338-B1 | Herbicidal compositions | BASF SE (DE) | 2011-05-25 | — | — | EP | disclosed |
| EP-2272342-A2 | Herbicidal compositions | BASF SE (DE) | 2011-01-12 | — | — | EP | disclosed |
| EP-2272341-A2 | Herbizide Zusammensetzungen | BASF SE (DE) | 2011-01-12 | — | — | EP | disclosed |
| US-5681793-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-28 | — | — | US | disclosed |
| US-5665673-A | SEMICARBAZONES | BASF AKTIENGESELLSCHAFT (DE) | 1997-09-09 | — | — | US | disclosed |
| US-5665674-A | SEMICARBAZONES | SANDOZ LTD. (CH) | 1997-09-09 | — | — | US | disclosed |
| US-5565410-A | 3-OXO-4-BENZOYL-5-OXY-2,3,4,6-TETRAHYDRO-1,2-OXAZINES; HERBICIDES; MITICIDES | SANDOZ LTD. (CH) | 1996-10-15 | — | — | US | disclosed |
| EP-0646315-A1 | Novel compositions containing an auxin transport inhibitor and another herbicide | SANDOZ LTD. (CH) | 1995-04-05 | — | — | EP | disclosed |
| EP-0614606-A2 | Herbicidal compositions | SANDOZ LTD. (CH) | 1994-09-14 | — | — | EP | disclosed |
| US-5336662-A | Herbicides | SANDOZ LTD. (CH) | 1994-08-09 | — | — | US | disclosed |
| EP-0394889-B1 | Heterocyclic diones as pesticides and plant growth regulators | SANDOZ AG (CH) | 1994-08-03 | — | — | EP | disclosed |
| EP-0394889-A2 | Heterocyclic diones as pesticides and plant growth regulators | SANDOZ AG (CH) | 1990-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140234225-A1 | METHOD OF TREATMENT USING NANOPARTICULATE COMPOSITIONS HAVING LYSOZYME AS A SURFACE STABILIZER | LPO, LCT, LIPA | SMN1; SMN2 2101/4885CYP2C19 751/4885POLB 1148/4885 |
| US-20130224123-A1 | NANOPARTICULATE COMPOSITIONS HAVING LYSOZYME AS A SURFACE STABILIZER | LPO, LCT, CTSA | SMN1; SMN2 2503/4885CYP2C19 712/4885POLB 1174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.