SCHEMBL8713872

SCHEMBL8713872

CC(Cc1ccc(O)cc1)(C[C@H](N)O)c1cccc(Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.42
ESR2 Q92731 4/20 0.42
KIF11 P52732 6/20 0.40
PNMT P11086 1/20 0.37
TAAR1 Q96RJ0 3/20 0.36
SLC6A2 P23975 1/20 0.36
PKM P14618 1/20 0.36
BLM P54132 1/20 0.35
CASR P41180 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8717072 0.90 KIF11 (0.40) KIF11PNMTSLC6A2PKMCASR
SCHEMBL8716173 0.90 KIF11 (0.40) ESR1ESR2KIF11PNMTSLC6A2
SCHEMBL8714910 0.88 KIF11 (0.43) KIF11PNMTTAAR1
SCHEMBL8716720 0.86 CASR (0.49) KIF11CASR
SCHEMBL8713560 0.85 KIF11 (0.42) KIF11PKM
SCHEMBL8714644 0.85 KIF11 (0.44) KIF11PKM
SCHEMBL8714176 0.85 MAOB (0.43) KIF11PKM
SCHEMBL8716326 0.84 PKM (0.49) KIF11PKM
SCHEMBL8714231 0.84 ESR1 (0.53) ESR1ESR2KIF11TAAR1SLC6A2
SCHEMBL8713306 0.84 KIF11 (0.40) KIF11PNMTTAAR1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5811293-A CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-09-22 US disclosed