Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 4/20 | 0.35 |
| ▸ | ACE | P12821 | 3/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717072 | 0.88 | KIF11 (0.40) | KIF11PNMT | |
| SCHEMBL8713872 | 0.88 | ESR1 (0.42) | KIF11TAAR1PNMT | |
| SCHEMBL8716173 | 0.88 | KIF11 (0.40) | KIF11PNMT | |
| SCHEMBL8713320 | 0.87 | ESR1 (0.38) | KIF11TAAR1MMEACE | |
| SCHEMBL8714644 | 0.86 | KIF11 (0.44) | KIF11 | |
| SCHEMBL8716720 | 0.84 | CASR (0.49) | KIF11 | |
| SCHEMBL8716326 | 0.84 | PKM (0.49) | KIF11MAOB | |
| SCHEMBL8714176 | 0.83 | MAOB (0.43) | KIF11MAOB | |
| SCHEMBL8713560 | 0.83 | KIF11 (0.42) | KIF11MAOB | |
| SCHEMBL8713306 | 0.81 | KIF11 (0.40) | KIF11TAAR1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |