Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.44 |
| ▸ | RXRA | P19793 | 4/20 | 0.43 |
| ▸ | RXRB | P28702 | 4/20 | 0.43 |
| ▸ | RXRG | P48443 | 3/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713560 | 0.91 | KIF11 (0.42) | KIF11PKM | |
| SCHEMBL8714176 | 0.91 | MAOB (0.43) | KIF11PKM | |
| SCHEMBL8714279 | 0.88 | KIF11 (0.40) | KIF11PKM | |
| SCHEMBL8719185 | 0.86 | KIF11 (0.43) | KIF11RXRARXRBRXRG | |
| SCHEMBL8713377 | 0.86 | KIF11 (0.39) | KIF11PKM | |
| SCHEMBL8714910 | 0.86 | KIF11 (0.43) | KIF11 | |
| SCHEMBL8717072 | 0.85 | KIF11 (0.40) | KIF11PKM | |
| SCHEMBL8713872 | 0.85 | ESR1 (0.42) | KIF11PKM | |
| SCHEMBL8716173 | 0.85 | KIF11 (0.40) | KIF11ADRB1PKM | |
| SCHEMBL8713274 | 0.85 | RAB9A (0.50) | KIF11PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |