Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711785 | 0.85 | CKS1B (0.35) | KDM4EALDH1A1RECQLPIK3CDSMN1; SMN2 | |
| SCHEMBL901425 | 0.82 | ALDH1A1 (0.38) | KDM4EALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL2300866 | 0.77 | CTSS (0.46) | KMT2AGAACTSSPOLB | |
| Leucine SCHEMBL8714828 | 0.72 | ALDH1A1 (0.37) | KDM4EALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL6800181 | 0.69 | ALDH1A1 (0.50) | KDM4EALDH1A1SMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL7445245 | 0.69 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KMT2AHSD17B10MEN1 | |
| SCHEMBL234783 | 0.68 | CTSS (0.59) | KMT2AGAACTSSPOLB | |
| SCHEMBL233988 | 0.68 | MMP2 (0.48) | KDM4EALDH1A1HSD17B10GAATSHR | |
| SCHEMBL3469950 | 0.68 | MMP2 (0.43) | KDM4EALDH1A1RENMAPTKMT2A | |
| SCHEMBL6799660 | 0.67 | ALDH1A1 (0.47) | KDM4EALDH1A1SMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788360-A4 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES | PROSCRIPT INC (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0788360-A1 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES | PROSCRIPT, INC. (US) | 1997-08-13 | — | — | EP | disclosed |