Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | RRM1 | P23921 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713645 | 0.83 | SIGMAR1 (0.44) | MAOBMAOASIGMAR1 | |
| SCHEMBL8430263 | 0.81 | SIGMAR1 (0.50) | MAOBMAOASIGMAR1 | |
| SCHEMBL8713821 | 0.80 | ALDH1A1 (0.45) | MEN1KMT2A | |
| SCHEMBL8713777 | 0.79 | MAOB (0.43) | MAOBMAOASIGMAR1 | |
| SCHEMBL8714022 | 0.77 | SIGMAR1 (0.43) | MAOBMAOAMEN1KMT2ASIGMAR1 | |
| SCHEMBL27735275 | 0.76 | MEN1 (0.47) | MAOBRRM1MEN1KMT2ACYP4F2 | |
| SCHEMBL8718156 | 0.76 | SIGMAR1 (0.42) | MAOAKMT2ASIGMAR1 | |
| SCHEMBL8716243 | 0.75 | ACHE (0.46) | KMT2ASIGMAR1 | |
| SCHEMBL8713177 | 0.75 | SIGMAR1 (0.40) | MAOBMAOASIGMAR1 | |
| SCHEMBL8714206 | 0.75 | SIGMAR1 (0.44) | MAOBMAOASIGMAR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |