Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | GUSB | P08236 | 2/20 | 0.36 |
| ▸ | EBP | Q15125 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 4/20 | 0.31 |
| ▸ | GBA1 | P04062 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719615 | 1.00 | GNAI3 (0.42) | GNAI3GNAO1GNAI1OPRM1OPRD1 | |
| SCHEMBL11242228 | 1.00 | GNAI3 (0.42) | GNAI3GNAO1GNAI1OPRM1OPRD1 | |
| SCHEMBL8717806 | 0.98 | GNAI3 (0.40) | GNAI3GNAO1GNAI1OPRM1OPRD1 | |
| SCHEMBL8714817 | 0.98 | GNAI3 (0.40) | GNAI3GNAO1GNAI1OPRM1OPRD1 | |
| SCHEMBL8714046 | 0.93 | SLC6A3 (0.35) | GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL8714043 | 0.93 | SLC6A3 (0.35) | GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL8714421 | 0.87 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL8714425 | 0.87 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL21755248 | 0.80 | OPRM1 (0.40) | GNAI3GNAO1GNAI1OPRM1OPRD1 | |
| SCHEMBL8715839 | 0.78 | PTGS1 (0.37) | GNAI3GNAO1GNAI1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708105-B1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0708105-A1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |