Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3298420 | 0.79 | TYMS (0.45) | HPGDKDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL8714067 | 0.78 | KDM4E (0.67) | HPGDKDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL15182506 | 0.75 | FABP4 (0.35) | HPGDKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL13736784 | 0.75 | KEAP1 (0.38) | HPGDKDM4EHSD17B10ALDH1A1MEN1 | |
| SCHEMBL20020909 | 0.75 | KDM4E (0.38) | HPGDKDM4EHSD17B10ALDH1A1POLB | |
| SCHEMBL20021160 | 0.72 | PRKCI (0.34) | HPGDKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL20021168 | 0.72 | PRKCI (0.37) | HPGDKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL15169189 | 0.70 | MAPK1 (0.31) | HPGDKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL1150917 | 0.69 | PARP1 (0.47) | HPGDKDM4EHSD17B10ALDH1A1NPSR1 | |
| SCHEMBL19389370 | 0.69 | ITGB2 (0.38) | LMNAHTTSMN1; SMN2PKMPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588455-B1 | 2-QUINOLINYL-ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS | GILEAD SCIENCES INC (US) | 2018-04-04 | — | — | EP | disclosed |