Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9094232 | 0.88 | LMNA (0.39) | SLC6A1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL9091831 | 0.88 | DRD1 (0.36) | SLC6A1GRIN2B | |
| SCHEMBL9095238 | 0.87 | SLC6A1 (0.37) | SLC6A1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL9229546 | 0.80 | GRIN2B (0.34) | SLC6A1GRIN2B | |
| SCHEMBL8716102 | 0.79 | SLC6A1 (0.65) | SLC6A1 | |
| SCHEMBL8718619 | 0.78 | LTA4H (0.52) | SLC6A1L3MBTL1 | |
| SCHEMBL8715436 | 0.78 | SLC6A1 (0.47) | SLC6A1 | |
| SCHEMBL8718270 | 0.78 | SLC6A1 (0.43) | SLC6A1GRIN1GRIN2BSIGMAR1 | |
| SCHEMBL8712827 | 0.76 | LTA4H (0.46) | SLC6A1SIGMAR1 | |
| SCHEMBL8715531 | 0.76 | HTR2C (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820442-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-01-28 | — | — | EP | disclosed |
| WO-1996031474-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | disclosed |