Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669690 | 0.95 | UTS2R (0.39) | CHRM1GAAUTS2RNPSR1HPGD | |
| SCHEMBL8502242 | 0.92 | NPSR1 (0.35) | CHRM1GAAUTS2RNPSR1HPGD | |
| SCHEMBL8665883 | 0.86 | NPSR1 (0.37) | CHRM1UTS2RNPSR1CCR2MCHR1 | |
| SCHEMBL8666099 | 0.84 | NPSR1 (0.36) | CHRM1UTS2RNPSR1CCR2MCHR1 | |
| SCHEMBL8501239 | 0.83 | NPSR1 (0.33) | CHRM1GAAUTS2RNPSR1HPGD | |
| SCHEMBL8480413 | 0.82 | TMEM97 (0.35) | GAA | |
| SCHEMBL8485545 | 0.81 | NPSR1 (0.40) | GAANPSR1MCHR1POLB | |
| SCHEMBL8501052 | 0.80 | NPSR1 (0.33) | CHRM1GAANPSR1HPGDCNR1 | |
| SCHEMBL8484461 | 0.79 | NPSR1 (0.39) | GAANPSR1MCHR1POLB | |
| SCHEMBL8668077 | 0.78 | OPRK1 (0.32) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739135-A | PREVENTING OR TREATING ATHEROSCLEROSIS, PANCREATITIS SECONDARY TO HYPERTRIGLYCERIDEMIA, HYPERGLYCEMIA, OBESITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | disclosed |