Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 5/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | BCR | P11274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709941 | 0.83 | L3MBTL1 (0.35) | L3MBTL1GAAMAPTALDH1A1KDM4E | |
| SCHEMBL17034855 | 0.68 | GAA (0.40) | GAAMAPTALDH1A1LMNAS1PR4 | |
| SCHEMBL8712772 | 0.66 | EGFR (0.36) | MAPTALDH1A1KDM4EPKMXDH | |
| SCHEMBL16654737 | 0.66 | L3MBTL1 (0.35) | L3MBTL1GAAMAPTALDH1A1KDM4E | |
| SCHEMBL2768003 | 0.65 | CYP3A4 (0.44) | L3MBTL1GAAMAPTALDH1A1KDM4E | |
| SCHEMBL8712930 | 0.65 | ALDH1A1 (0.32) | GAAMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL17625677 | 0.62 | ALDH1A1 (0.46) | L3MBTL1MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL21608245 | 0.61 | MAPK1 (0.37) | ALDH1A1KDM4ELMNA | |
| SCHEMBL21608244 | 0.61 | MAPK1 (0.37) | ALDH1A1KDM4ELMNA | |
| SCHEMBL21598726 | 0.61 | MAPK1 (0.37) | ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716971-A | FOR TREATMENT OF ANGINA PECTORIS AND HYPERTENSION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |