Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405894 | 0.78 | CA1 (0.54) | CA1CA2ALDH1A1MAPTLMNA | |
| SCHEMBL13468496 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNAPOLBHTT | |
| SCHEMBL7777861 | 0.76 | POLB (0.43) | CA1CA2ALDH1A1MAPTLMNA | |
| SCHEMBL8720708 | 0.74 | TBXA2R (0.41) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL8720077 | 0.73 | KMT2A (0.39) | ALDH1A1MAPTLMNAPOLBHTT | |
| SCHEMBL9383997 | 0.72 | NR1H2 (0.35) | CA1CA2ALDH1A1MAPTLMNA | |
| SCHEMBL128275 | 0.72 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL4215466 | 0.71 | BRD4 (0.41) | ALDH1A1MAPTLMNAPOLBHTT | |
| SCHEMBL2807827 | 0.70 | PAK1 (0.36) | CA1CA2ALDH1A1MAPTLMNA | |
| SCHEMBL31564202 | 0.70 | DRD2 (0.47) | GRIN2BAKR1C3DRD2DRD3MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739132-A | ENDOTHOXIN SHOCK; NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0579059-A1 | Pyridazinone derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |