Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | POLB | P06746 | 5/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9383997 | 0.81 | NR1H2 (0.35) | KMT2APOLBBRD4MEN1SLC26A4 | |
| SCHEMBL8715129 | 0.73 | CA1 (0.41) | KMT2APOLBBRD4PKMLMNA | |
| SCHEMBL8720708 | 0.71 | TBXA2R (0.41) | KMT2AMEN1RAB9ALMNANR1H2 | |
| SCHEMBL7777861 | 0.67 | POLB (0.43) | KMT2APOLBBRD4MEN1PKM | |
| SCHEMBL10405894 | 0.67 | CA1 (0.54) | KMT2APOLBBRD4MEN1PKM | |
| SCHEMBL9414927 | 0.67 | PNMT (0.40) | PKMPNMTSMN1; SMN2 | |
| SCHEMBL2807827 | 0.66 | PAK1 (0.36) | KMT2APOLBBRD4PKMLMNA | |
| SCHEMBL13468496 | 0.66 | ALDH1A1 (0.56) | KMT2APOLBBRD4MEN1PKM | |
| SCHEMBL8715076 | 0.64 | BRD4 (0.34) | KMT2APOLBBRD4MEN1PKM | |
| SCHEMBL4623414 | 0.62 | BRD4 (0.55) | KMT2APOLBBRD4MEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739132-A | ENDOTHOXIN SHOCK; NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0579059-A1 | Pyridazinone derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |