Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 0.43 |
| ▸ | HTR2A | P28223 | 14/20 | 0.43 |
| ▸ | DRD3 | P35462 | 14/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549267 | 0.82 | DRD2 (0.46) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL8708816 | 0.79 | DRD2 (0.47) | DRD2HTR2ADRD3SLC6A4 | |
| Hydrochloric Acid SCHEMBL8710593 | 0.75 | CHRM4 (0.42) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL8703223 | 0.74 | DRD2 (0.46) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL8551530 | 0.73 | DRD2 (0.54) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL8552921 | 0.73 | DRD2 (0.49) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL8548622 | 0.73 | DRD2 (0.47) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL8551606 | 0.73 | DRD2 (0.51) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL8552841 | 0.72 | KMT2A (0.47) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL8551604 | 0.72 | UBE2M (0.49) | DRD2HTR2ADRD3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |