Mandelic Acid

Mandelic Acid

SCHEMBL8715339

O=C(O)C(O)c1ccccc1.Oc1ccc(O)cc1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.82
MAPK1 P28482 1/20 0.82
CES2 O00748 2/20 0.54
CES1 P23141 1/20 0.54
SRC P12931 3/20 0.50
CYP2D6 P10635 1/20 0.50
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 2/20 0.44
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
IDO1 P14902 1/20 0.44
TDO2 P48775 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
GLA P06280 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mandelic Acid SCHEMBL28078527 0.95 LMNA (0.82) LMNAMAPK1CES2CES1SRC
SCHEMBL1957930 0.91 LMNA (0.65) LMNAMAPK1CES2CES1SRC
SCHEMBL467741 0.91 LMNA (0.65) LMNAMAPK1CES2CES1SRC
SCHEMBL352555 0.91 LMNA (0.65) LMNAMAPK1CES2CES1SRC
SCHEMBL31484031 0.91 LMNA (0.65) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL5313046 0.91 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL165161 0.91 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL21647917 0.91 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL29777368 0.91 LMNA (1.00) LMNAMAPK1CES2CES1SRC
Mandelic Acid SCHEMBL255601 0.91 LMNA (1.00) LMNAMAPK1CES2CES1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0873444-A1 ENZYMATIC METHOD FOR TEXTILE DYEING Novo Nordisk Biochem North America (US) 1998-10-28 EP disclosed
WO-1997023685-A1 ENZYMATIC METHOD FOR TEXTILE DYEING NOVO NORDISK BIOCHEM NORTH AMERICA, INC. (US) 1997-07-03 WO disclosed