Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718492 | 0.87 | MAPT (0.42) | MTNR1AKMT2AGLAMEN1CYP3A4 | |
| SCHEMBL8717599 | 0.82 | MTNR1A (0.35) | MTNR1AALDH1A1MAPTL3MBTL1HPGD | |
| SCHEMBL8713402 | 0.82 | ALDH1A1 (0.36) | MTNR1AKMT2AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL8715401 | 0.79 | KMT2A (0.40) | MTNR1AKMT2AGLAMEN1CYP3A4 | |
| SCHEMBL8716330 | 0.76 | FOLH1 (0.40) | MTNR1AKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL8719530 | 0.76 | ALDH1A1 (0.40) | MTNR1AKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL7346730 | 0.73 | AVPR1A (0.62) | — | |
| SCHEMBL8715310 | 0.73 | ALDH1A1 (0.46) | KMT2AMEN1GAAALDH1A1MAPT | |
| SCHEMBL8713941 | 0.72 | POLB (0.41) | KMT2AMEN1NPSR1GAAALDH1A1 | |
| SCHEMBL8714612 | 0.71 | ALDH1A1 (0.51) | KMT2AMEN1NPSR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |