Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715140 | 0.89 | HDAC3 (0.38) | POLBLMNAGAAALDH1A1TP53 | |
| SCHEMBL8717614 | 0.87 | KMT2A (0.41) | POLBLMNAGAAALDH1A1NPC1 | |
| SCHEMBL8718454 | 0.83 | ALDH1A1 (0.48) | LMNAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8716872 | 0.82 | POLB (0.45) | POLBLMNAALDH1A1HPGD | |
| SCHEMBL8715310 | 0.80 | ALDH1A1 (0.46) | POLBGAAALDH1A1NPC1KMT2A | |
| SCHEMBL8714612 | 0.78 | ALDH1A1 (0.51) | POLBLMNAALDH1A1NPSR1NPC1 | |
| SCHEMBL8714945 | 0.77 | KMT2A (0.57) | LMNAALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL8718492 | 0.77 | MAPT (0.42) | LMNAALDH1A1TP53KMT2AMEN1 | |
| SCHEMBL8713944 | 0.77 | NPC1 (0.41) | POLBLMNAALDH1A1NPSR1NPC1 | |
| SCHEMBL8718123 | 0.74 | TAOK1 (0.51) | POLBGAAALDH1A1NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |