Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713941 | 0.80 | POLB (0.41) | ALDH1A1POLBNPC1GAAMEN1 | |
| SCHEMBL8718492 | 0.78 | MAPT (0.42) | ALDH1A1KDM4EMAPTL3MBTL1MEN1 | |
| SCHEMBL8716872 | 0.78 | POLB (0.45) | ALDH1A1KDM4EPOLBMAPTL3MBTL1 | |
| SCHEMBL8714612 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KDM4EPOLBMAPTNPC1 | |
| SCHEMBL8715140 | 0.76 | HDAC3 (0.38) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL8717599 | 0.75 | MTNR1A (0.35) | ALDH1A1KDM4EPOLBMAPTCHRM2 | |
| SCHEMBL8713402 | 0.75 | ALDH1A1 (0.36) | ALDH1A1KDM4EPOLBMAPTCHRM2 | |
| SCHEMBL8717614 | 0.75 | KMT2A (0.41) | ALDH1A1POLBMAPTNPC1GAA | |
| SCHEMBL8718123 | 0.75 | TAOK1 (0.51) | ALDH1A1KDM4EPOLBMAPTNPC1 | |
| SCHEMBL8714945 | 0.75 | KMT2A (0.57) | ALDH1A1MAPTNPC1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |