Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 7/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | UGCG | Q16739 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904008 | 0.86 | CETP (0.43) | DRD2RAB9ANPC1DRD3DRD4 | |
| SCHEMBL8715642 | 0.86 | CETP (0.43) | DRD2RAB9ANPC1DRD3DRD4 | |
| SCHEMBL8904810 | 0.84 | ITGB3 (0.48) | DRD2RAB9ANPC1HTR2AHTR1A | |
| SCHEMBL8904025 | 0.84 | DRD2 (0.45) | DRD2DRD3HTR2AMCHR1 | |
| SCHEMBL8717762 | 0.84 | ITGB3 (0.48) | DRD2RAB9ANPC1HTR2AHTR1A | |
| SCHEMBL8904717 | 0.76 | RAB9A (0.40) | DRD2RAB9ANPC1HTR2AHTR1A | |
| SCHEMBL8904718 | 0.76 | RAB9A (0.40) | DRD2RAB9ANPC1HTR2AHTR1A | |
| SCHEMBL8715492 | 0.75 | ITGB3 (0.50) | DRD2RAB9ANPC1HTR2AHTR1A | |
| SCHEMBL8715681 | 0.73 | MAPT (0.46) | DRD2RAB9ANPC1DRD3DRD4 | |
| SCHEMBL23920230 | 0.73 | ACACB (0.48) | RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753670-A | ANTICOAGULANTS | THE GREEN CROSS CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |