Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 16/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL871941 | 0.85 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL8606048 | 0.85 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL8040636 | 0.85 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL5313076 | 0.84 | SLC6A3 (0.51) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL15065354 | 0.83 | LMNA (0.43) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL872384 | 0.83 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL15066051 | 0.82 | SLC6A4 (0.48) | SLC6A3SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL10761073 | 0.82 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL15065680 | 0.82 | LMNA (0.42) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL5086480 | 0.81 | SLC6A3 (0.59) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104039753-B | The compositions of phenylcycloalkyl methylamine derivative, synthesis and using method | 雷维瓦药品公司 | 2016-09-14 | — | — | CN | disclosed |
| WO-2012003501-A2 | COMPOSITIONS, SYNTHESIS, AND METHODS OF USING CYCLOALKYLMETHYLAMINE DERIVATIVES | REVIVA PHARMACEUTICALS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |