Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL871578 | 0.83 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL872307 | 0.77 | SLC6A3 (0.61) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL13458445 | 0.76 | SLC6A4 (0.53) | SLC6A3SLC6A4SLC6A2HTR2AHTR2C | |
| SCHEMBL872817 | 0.76 | SLC6A3 (0.39) | SLC6A3SLC6A4SLC6A2HTR2A | |
| SCHEMBL15065638 | 0.75 | CASP1 (0.49) | SLC6A3SLC6A4SLC6A2ALDH1A1 | |
| SCHEMBL7196726 | 0.75 | SLC6A3 (0.64) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL871941 | 0.74 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2HTR2AHTR2B | |
| SCHEMBL8606048 | 0.74 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2HTR2AHTR2B | |
| SCHEMBL8040636 | 0.74 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2HTR2AHTR2B | |
| SCHEMBL12000528 | 0.74 | SLC6A4 (0.58) | SLC6A3SLC6A4SLC6A2KDM1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003501-A2 | COMPOSITIONS, SYNTHESIS, AND METHODS OF USING CYCLOALKYLMETHYLAMINE DERIVATIVES | REVIVA PHARMACEUTICALS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |