Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716302 | 0.83 | — | — | |
| SCHEMBL8715796 | 0.80 | ESR1 (0.36) | SMN1; SMN2TDP1 | |
| SCHEMBL8473093 | 0.73 | ABCC8 (0.44) | HCAR3GLP1R | |
| SCHEMBL7069196 | 0.70 | ABCC8 (0.33) | HCAR3ALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL7067993 | 0.70 | ABCC8 (0.33) | HCAR3ALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL7067998 | 0.70 | ABCC8 (0.33) | HCAR3ALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL8721026 | 0.65 | ALDH1A1 (0.33) | HCAR3ALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL8716367 | 0.64 | ALDH1A1 (0.36) | HCAR3ALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL7074936 | 0.62 | ABCC8 (0.46) | HCAR3ALDH1A1GLP1R | |
| SCHEMBL7074933 | 0.62 | ABCC8 (0.46) | HCAR3ALDH1A1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876379-A1 | FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997026265-A1 | FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-07-24 | — | — | WO | disclosed |