⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640743 | 0.73 | EPHX2 (0.30) | — | |
| SCHEMBL8662788 | 0.72 | SNCA (0.35) | — | |
| SCHEMBL16974832 | 0.71 | — | — | |
| SCHEMBL8582748 | 0.71 | — | — | |
| SCHEMBL8584298 | 0.71 | — | — | |
| SCHEMBL8639052 | 0.69 | NOX1 (0.43) | — | |
| SCHEMBL8642024 | 0.68 | HCAR3 (0.43) | — | |
| SCHEMBL7161005 | 0.68 | KAT2B (0.36) | — | |
| SCHEMBL7004764 | 0.67 | ABCC8 (0.31) | — | |
| SCHEMBL7067583 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876379-A1 | FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997026265-A1 | FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-07-24 | — | — | WO | disclosed |