Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121263 | 0.84 | MAOA (0.49) | CYP1A2MAOAKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL7628834 | 0.83 | ALDH1A1 (0.47) | LMNAKDM4EAHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL1511820 | 0.82 | KDM4E (0.51) | LMNAKDM4ESMN1; SMN2ALDH1A1GAA | |
| SCHEMBL29120037 | 0.81 | CYP4F2 (0.50) | CYP1A2KDM4EAHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL8713685 | 0.80 | SMN1; SMN2 (0.40) | LMNAKDM4EAHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9684011 | 0.79 | KDM4E (0.52) | LMNACYP1A2KDM4EAHRSMN1; SMN2 | |
| SCHEMBL9216355 | 0.77 | AKR1B1 (0.38) | KDM4EAHRSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8718013 | 0.76 | SMN1; SMN2 (0.37) | KDM4EAHRSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL11453854 | 0.76 | MMP2 (0.37) | KDM4EAHRAKR1B1 | |
| SCHEMBL11465382 | 0.75 | PRKCZ (0.45) | LMNACYP1A2KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753670-A | ANTICOAGULANTS | THE GREEN CROSS CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |